目的 探讨胼周脂肪瘤产前超声特征并与生后影像及病理对照分析，以提高对此类畸形的认识。方法 回顾性分析湖北省妇幼保健院2015年1月至2018年1月经病理或生后影像证实的5例胼周脂肪瘤产前超声及MR声像图特征，并与出生后病理及影像对照分析。结果 5例均行产前超声检查，其中4例行产前MR检查；3例引产后行病理检查，2例出生后定期行MR及CT检查。3例男婴，2例女婴。5例产前超声表现：①均于晚孕期发现中线部位强回声光团（光团形态不规则，主体为管结节形，无明确边界，无包膜），2例单发，3例向侧脑室延伸，2例光团内部有血流信号显示；②5例中2例胼胝体缺如伴双侧侧脑室增宽；③1例诊断颅内出血，1例诊断为畸胎瘤，3例诊断为脂肪瘤。4例产前MR表现：①均在T1W与T2W上发现中线部位高信号及稍高信号；②均发现胼胝体发育不良，其中2例胼胝体缺如与超声诊断一致；③2例诊断颅内出血，2例诊断为脂肪瘤。3例引产后病理检查：2例肿块内为脂肪组织，1例肿块内除脂肪组织外还有软骨及钙化成分。2例出生后定期行MR和CT检查，1例生后1岁内CT、MR检查发现有钙化，诊断为畸胎瘤，2岁后CT、MR复查会诊为胼周脂肪瘤；1例生后CT、MR检查诊断胼周脂肪瘤。结论 胼周脂肪瘤产前超声有特征性的表现，结合MR可提高诊断率。
Objective To explore the characteristics of prenatal ultrasound imaging of pericallosal lipoma and to compare with postnatal imaging and pathology to improve the understanding of such malformations. Methods The characteristics of prenatal ultrasound and MR images of 5 cases of pericallosal lipoma confirmed by pathology or postnatal imaging from January 2015 to January 2018 in hubei provincial maternal and child health hospital were retrospectively analyzed, and compared with postnatal pathology and imaging. Results Postpartum pathology or imaging confirmed pericallosal lipoma in 5 cases, and prenatal ultrasonic examination was performed in 5 case,prenatal MR examination was performed in 4 cases，pathological examination was performed in 3 cases after labor induction, and MR and CT examinations were performed regularly in 2 cases after birth. Three were male and two were female. Prenatal ultrasound findings in 5 cases：①All of them were found to have a strong echogenic light mass at the midline in late pregnancy（The shape of light mass is irregular, the tumor body is tubular nodular, without clear boundary and capsule.Two cases were solitary, three cases extended to the lateral ventricle, and two cases had blood flow signal in the light mass. ②Absence of corpus callosum was associated with bilateral lateral ventricular enlargement in 2 of the 5 patients. ③Intracranial hemorrhage was diagnosed in 1 patient, teratoma in 1 patient, and lipoma in 3 patients. Prenatal MR findings in 4 cases：①High signal and slightly high signal were found in the middle line on. ②Dysplasia of corpus callosum was found in all cases, and the absence of corpus callosum in 2 cases was consistent with the ultrasonic diagnosis.③Intracranial hemorrhage was diagnosed in 2 cases. Two cases were diagnosed as lipoma. Pathological examination of 3 cases after labor induction：There were adipose tissue in 2 patients and cartilage and calcification in 1 patient. MR and CT examinations were performed regularly in 2 cases after birth,One case was diagnosed as teratoma by CT and MR examination within 1 year after birth, and was diagnosed as subcallus lipoma by CT and MR reexamination after 2 years；Postnatal CT and MR examination were performed in 1 patient for the diagnosis of pericallosal lipoma. Conclusions The prenatal ultrasound of pericallosal lipoma showed characteristic manifestations, and combined with MR could improve the diagnostic rate.
