产前超声诊断单脐动脉、持续性右脐静脉胎儿与畸形的关系探讨 [中文引用][英文引用]

目的  探讨产前多普勒超声诊断单脐动脉、持续性右脐静脉胎儿与畸形的关系。方法  对产前超声诊断的163例单脐动脉和64例持续性右脐静脉胎儿合并畸形情况进行回顾性分析。结果 ①单脐动脉胎儿163例，合并畸形48例，畸形检出率29．4％（48/163）。其中心脏异常16例，神经系统异常11例，泌尿生殖系统异常11例，骨骼及肢体异常6例，颜面部异常3例，胸部异常4例，消化系统异常2例。②持续性右脐静脉胎儿64例，合并畸形16例，畸形检出率25％（16/64）。其中心脏异常6例，骨骼及肢体异常5例，神经系统异常、胸部异常、消化系统异常各3例，泌尿生殖系统异常1例。③单脐动脉与持续性右脐静脉同时存在1例，合并有心脏及肺部发育异常。结论 单脐动脉、持续性右脐静脉胎儿，具有合并畸形的高风险性，产前超声检查是首要的检查方法，有重要临床意义。

Objective  To reesearch the relationship of single umbilical artery, persistent right umbilical vein and fetal malformations. Method  A retrospective analysis was made on prenatal ultrasound diagnosis of 163 patients with single umbilical artery and 64 cases with persistent right umbilical vein of fetal malformations. Results  ①Checking 163 cases of single umbilical artery of fetuses, merging other malformations has 48 cases. Checking out rates is 29.4 %（48/163）.In which,16 cases of abnormal cardiac abnormalities, 11 cases of abnormal nervous system, 11 cases of genitourinary system, 6 cases of bones and limb abnormalities, 3 cases of facial abnormalities, 4 cases of chest abnormal, 2 cases of digestive abnormalities. ②Checking 64 cases of persistence the right umbilical vein of fetuses. Merging other malformations has 16 cases, checking out rates is 25%（16/64）in which, 6 cases of cardiac abnormalities, 5 cases of skeletal and limb abnormalities, 3 cases of neurological abnormalities, 3 cases of chest abnormalities, 3 cases of digestive abnormalities, 1 case of the genitourinary system anomalies. ③Single umbilical artery and persistent right umbilical vein exist simultaneously in 1 case, combined with cardiac and pulmonary dysplasia.  Conclusions  Single umbilical artery and persistence the right umbilical vein fetuses had high risks rate of merging other malformations. Prenatal ultrasonography is a reliable and effective method in finding feta single umbilical, persistent right umbilical vein and merging other malformations. It is very impotant in clinic trials.