Objective To determine prevalence and type of chromosomal abnormalities in spontaneous abortion, and explore the correlation between them. Method Abortion tissues were obtained under aseptic conditions, and detected by conventional cytogenetic analysis and FISH. Results 66 abnormalities were detected in 136 cases, and the abnormal detection rate was 48.53%.The predominant chromosomal aberrations are trisomies (45.45%), triploidy (25.76%) and monosomy (18.18%). Conclusions Chromosomal abnormality is the main reason of spontaneous abortion. It is necessary to detect chromosome of spontaneous abortion tissues.
